Indus Impex

It is a muscle relaxant, prescribed for spasticity and muscle spasms.

Tolperisone is a centrally acting muscle relaxant.

Product Name: Numbon 2% Gel
Active Ingredient: Lignocaine Hydrochloride 2% w/w
Manufacturer: American Remedies
Packing Size: 30 grams (Net weight 10 gm tube inside 30 g packing)
Exporter: Indus Impex

Description:
Numbon 2% Gel contains Lignocaine Hydrochloride, a fast-acting local anesthetic that provides effective topical pain relief by blocking nerve signals in the body. It is used to numb specific areas before minor procedures or to relieve pain, itching, and discomfort caused by conditions such as minor burns, insect bites, or hemorrhoids.

Uses:

• Topical anesthesia before minor medical or dental procedures

• Relief of pain, itching, or discomfort from minor skin irritations

• Management of symptoms related to hemorrhoids, sunburns, insect bites, and sore gums

Key Features:

• Rapid onset of numbing action

• Smooth, easy-to-apply gel formulation

• Provides localized pain relief

• Suitable for dermatological and dental use (as directed by a doctor)

Directions for Use:

• Apply a small amount of Numbon 2% Gel to the affected area.

• Massage gently until absorbed.

• Use as directed by a healthcare provider.

• Avoid applying to large areas or broken skin unless directed.

Precautions:

• For external use only

• Avoid contact with eyes; rinse immediately if contact occurs

• Do not use on deep wounds or serious burns without medical advice

• Consult a doctor before use during pregnancy or breastfeeding

Uses:

Paracetamol is used for the relief of mild to moderate pain in conditions as headache (including migraine), toothache, ear pain, joint pain, pain during menstruation, fever, feverish colds, flu.

Abnormal blood cell counts, Blisters., Runny nose, nausea., Skin reddening, Rare: allergic reactions as shortness of breath, Swollen facial features, Liver damage, Abnormalities of blood cells.

Uses:

• Systemically attacks the root cause of inflammatory disorders in joints & muscles.
• Normalizes the physiological parameters to bring about improved blood circulation & fuctional improvement.
• Reduces morning stiffness, increase mobility and grip strength,restores co-ordination.
• Effectively checks joint erosion.
• Produces regression & lasting relief in rheumatic conditions.

Indication :

All types acute and chronic muscular and joint pains, Rheumatic and Arthritic conditions, Neuralgia, Myalgia, Lumbago, Gout, Sciatica, Spondylitis, Tendinitis, Bursitis etc.
Ingredients:

Mahayograj Guggul, Sameerpannag, Rasna, Khuasani Owa, Chitrak, Nirgundi, Kundru.

• Mahayograj Guggul : Possesses anti-inflammatory,anti-Rasna,Kundru & Rheumatic actions.
• Sameerpannag : Strengthens muscles,tendons & ligaments.
  Potentiates anti-inflammatory effects of other drugs.
• Kundru : Restores integrity of vascular blood vessels,builds collaterals.
• Khurasani Owa : Muscle relaxant.
• Chitrak : Promotes tissue metabolism & prevents formation of ama.

It blocks the release of chemicals in the body cause inflammation.

Baclofen tablets are a prescription medication used primarily to treat muscle spasms caused by certain conditions such as multiple sclerosis, spinal cord injuries, or other neurological disorders. Baclofen belongs to the class of medications known as muscle relaxants, and it works by acting on the central nervous system to reduce muscle hyperactivity and stiffness. Here are some key points about Baclofen tablets:

1. Muscle Relaxation: Baclofen tablets are effective in relieving muscle spasms, cramping, and tightness associated with various neurological conditions. By targeting the central nervous system, Baclofen helps to inhibit the transmission of signals that cause muscles to contract excessively, resulting in relaxation and improved mobility.

2. Dosage Forms: Baclofen is available in tablet form for oral administration. Each tablet typically contains a specific dosage of baclofen, commonly ranging from 5mg to 20mg, although dosages may vary depending on the individual's medical condition and response to treatment.

3. Indications: Baclofen tablets are indicated for the treatment of spasticity, a condition characterized by involuntary muscle contractions and stiffness. Spasticity can occur as a result of various neurological disorders, including multiple sclerosis, cerebral palsy, spinal cord injuries, and stroke. Baclofen may also be used off-label for other conditions such as hiccups or alcohol withdrawal syndrome.

4. Dosage and Administration: The dosage of Baclofen tablets varies depending on the severity of the muscle spasms and the individual's response to treatment. It is typically initiated at a low dose and gradually increased as needed under the supervision of a healthcare professional. The tablets are usually taken orally, with or without food, several times a day, as prescribed by the physician.

5. Safety and Side Effects: While generally well-tolerated, Baclofen tablets may cause side effects in some individuals. Common side effects may include drowsiness, dizziness, weakness, fatigue, nausea, and headache. It is important to avoid activities that require mental alertness, such as driving or operating heavy machinery, until the effects of Baclofen on the individual are known. Serious side effects such as hallucinations, seizures, or allergic reactions are rare but should be reported to a healthcare provider immediately.

6. Precautions and Contraindications: Baclofen should be used with caution in individuals with a history of kidney impairment, psychiatric disorders, or seizures. It is contraindicated in patients with hypersensitivity to baclofen or any of the tablet's components. Baclofen may also interact with certain medications, so it is essential to inform the prescribing healthcare provider of all medications, supplements, and medical conditions before starting treatment.

7. Discontinuation: Baclofen treatment should not be abruptly discontinued, as this may lead to withdrawal symptoms such as hallucinations, seizures, or rebound spasticity. It is important to follow the physician's instructions for tapering off the medication gradually if discontinuation is necessary.

Baclofen tablets are a valuable therapeutic option for the management of muscle spasms and spasticity associated with neurological conditions. When used as directed and under the supervision of a healthcare professional, Baclofen can help improve mobility, reduce discomfort, and enhance quality of life for individuals affected by these conditions.

Baricitinib tablets are a prescription medication used in the treatment of moderate to severe rheumatoid arthritis (RA) in adult patients who have not responded well to other disease-modifying antirheumatic drugs (DMARDs). Baricitinib belongs to a class of medications known as Janus kinase (JAK) inhibitors, which work by inhibiting specific enzymes involved in the inflammatory process. Here are some key points about Baricitinib tablets:

1. Treatment of Rheumatoid Arthritis: Baricitinib tablets are indicated for the treatment of moderate to severe rheumatoid arthritis in adult patients who have had an inadequate response or intolerance to one or more DMARDs. Rheumatoid arthritis is a chronic autoimmune disease that causes inflammation, pain, stiffness, and joint damage.

2. Mode of Action: Baricitinib inhibits the activity of Janus kinases (JAKs), particularly JAK1 and JAK2, which are enzymes involved in the signaling pathways of pro-inflammatory cytokines such as interleukin-6 (IL-6) and interferon-gamma (IFN-γ). By blocking these pathways, Baricitinib helps reduce inflammation and slow the progression of joint damage in rheumatoid arthritis.

3. Dosage Forms: Baricitinib is available in tablet form for oral administration. Each tablet typically contains a specific dosage of Baricitinib, commonly ranging from 1 mg to 4 mg, although dosages may vary depending on the individual's disease severity and response to treatment.

4. Dosage and Administration: The recommended dosage of Baricitinib tablets for the treatment of rheumatoid arthritis is usually 2 mg once daily, taken orally with or without food. However, dosage adjustments may be necessary based on the patient's response to treatment and any concomitant medications being taken. It is important to follow the prescribed dosage regimen as directed by a healthcare professional.

5. Safety and Side Effects: While generally well-tolerated, Baricitinib tablets may cause side effects in some individuals. Common side effects may include upper respiratory tract infections, nausea, headache, and hypertension. Serious side effects such as increased risk of infections, thrombosis, liver enzyme elevations, and gastrointestinal perforations are possible and require monitoring by a healthcare provider.

6. Monitoring and Precautions: Before initiating treatment with Baricitinib, healthcare providers may perform baseline laboratory tests and assess the patient's medical history to identify any risk factors or contraindications. Regular monitoring of blood counts, liver function, and lipid levels may be necessary during treatment.

7. Contraindications: Baricitinib tablets are contraindicated in patients with a history of hypersensitivity to Baricitinib or any of its components. It should not be used in combination with other JAK inhibitors or biologic DMARDs.

Baricitinib tablets offer a targeted treatment option for adult patients with moderate to severe rheumatoid arthritis who have not responded adequately to other DMARDs. When used as directed and under the supervision of a healthcare professional, Baricitinib can help reduce inflammation, relieve symptoms, and improve the overall quality of life for individuals living with rheumatoid arthritis.

Brilinta- Brilinta (ticagrelor) helps to prevent platelets in your blood from sticking together and forming a blood clot. An unwanted blood clot can occur with certain heart or blood vessel conditions.

Brilinta is used to lower your risk of having a stroke or serious heart problems after you have had a heart attack or severe chest pain (angina).

• It is used in combination with pain killers to ease pain that includes headache, migraine, neuralgia, toothache, sore throat, period pains, relief of sprains, strains, rheumatic pain, muscular aches and pains, joint swelling and stiffness, influenza, feverishness and feverish colds.
• It is used to treat absence of breathing seen in newborns.

• It is used for the short-term treatment of mild to moderate pain from various conditions.
• It is also used to decrease pain and blood loss from menstrual periods.

• Upset stomach, nausea, heartburn, dizziness, drowsiness, diarrhea, and headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Dexamethasone is a potent synthetic corticosteroid medication that mimics the action of naturally occurring hormones in the body. It belongs to a class of drugs known as glucocorticoids, which have anti-inflammatory, immunosuppressive, and anti-allergic properties. Here are some key points about dexamethasone:

1. Indications: Dexamethasone is used to treat a variety of medical conditions, including inflammatory disorders, autoimmune diseases, allergic reactions, and certain types of cancer. Common indications for dexamethasone include:

   • Inflammatory conditions such as rheumatoid arthritis, lupus, and inflammatory bowel disease.
   • Allergic conditions such as asthma, allergic rhinitis, and dermatitis.
   • Immune system disorders such as multiple sclerosis and graft-versus-host disease.
   • Certain types of cancer, including leukemia, lymphoma, and multiple myeloma.

2. Mechanism of Action: Dexamethasone exerts its therapeutic effects by binding to glucocorticoid receptors in target cells, leading to changes in gene expression and modulation of various cellular processes. It suppresses inflammation by inhibiting the production of pro-inflammatory cytokines and mediators, reducing the migration of inflammatory cells, and stabilizing cell membranes.

3. Dosage Forms: Dexamethasone is available in various dosage forms, including tablets, oral solutions, injections, eye drops, and topical creams or ointments. The choice of dosage form depends on the specific medical condition being treated and the route of administration preferred by the healthcare provider.

4. Dosage and Administration: The dosage of dexamethasone varies depending on the type and severity of the medical condition being treated, as well as the individual patient's response to treatment. It is usually administered orally, intravenously, or topically, with dosages adjusted over time based on the patient's clinical response and any adverse effects observed.

5. Safety and Side Effects: While generally effective in treating a wide range of conditions, dexamethasone can cause side effects, particularly with long-term or high-dose use. Common side effects may include fluid retention, weight gain, high blood pressure, mood changes, insomnia, and gastrointestinal symptoms. Long-term use of dexamethasone may also increase the risk of osteoporosis, diabetes, and immunosuppression.

6. Precautions and Contraindications: Dexamethasone should be used with caution in patients with a history of diabetes, hypertension, glaucoma, or peptic ulcer disease. It is contraindicated in patients with systemic fungal infections or hypersensitivity to dexamethasone or any of its components. Dexamethasone should be used during pregnancy only if the potential benefits justify the potential risks to the fetus.

Dexamethasone is a versatile medication with broad therapeutic applications in the treatment of various inflammatory, autoimmune, and allergic conditions, as well as certain types of cancer. When used appropriately and under the guidance of a healthcare professional, dexamethasone can help alleviate symptoms, reduce inflammation, and improve the quality of life for patients affected by these conditions.

Product Name: Lignocaine Spray
Composition: Lignocaine (Lidocaine)
Strength: As per standard (typically 10%)
Packaging Size: 15 gm Spray Bottle
Form: Topical Aerosol Spray
Usage/Application: Local Anaesthesia / Numbing Spray
Category: Anaesthetic Spray / Pain Relief

Lignocaine Spray 15gm is a fast-acting topical anaesthetic spray containing Lignocaine (Lidocaine), widely used for temporary numbing of mucous membranes and minor surgical or dental procedures. This convenient aerosol form ensures quick absorption and effective pain relief at the site of application.

✅ Contains Lignocaine – a proven local anaesthetic agent
✅ 15 gm spray bottle for ease of use and portability
✅ Provides rapid numbing effect for targeted pain relief
✅ Commonly used in dental, ENT, urology, and minor skin procedures
✅ Non-invasive, convenient, and hygienic application

• Relief of pain during dental procedures

• Local anaesthesia for minor surgical or diagnostic procedures

• Surface anaesthesia of the skin and mucous membranes

• Shake well before use

• Spray directly on the affected area as directed by a healthcare provider

• Avoid contact with eyes

Store in a cool, dry place below 30°C. Protect from direct sunlight and heat.

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Uses:

Supamove (marketed as Voltaren and under a number of other trade names, see below) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in conditions such as arthritis or acute injury. It can also be used to reduce menstrual pain, dysmenorrhea. The name is derived from its chemical name: 2-(2,6-dichloranilino)phenylacetic acid.

In the United Kingdom, India, and the United States, it may be supplied as either the sodium or potassium salt, in China most often as the sodium salt, while in some other countries only as the potassium salt. Supamove is available as a generic drug in a number of formulations. Over the counter (OTC) use is approved in some countries for minor aches and pains and fever associated with common infections.

Indomax 25 mg is a nonsteroidal anti-inflammatory drug (NSAID) containing indomethacin, used to relieve pain, inflammation, and swelling in conditions like arthritis, gout, and joint disorders. It works by reducing substances in the body that cause inflammation.

Here's a description of Indomethacin Capsule IP 25mg:

Purpose: Indomethacin Capsule IP 25mg is used to reduce pain, inflammation, and swelling associated with conditions such as rheumatoid arthritis, osteoarthritis, gouty arthritis, ankylosing spondylitis, and certain types of acute musculoskeletal pain.

Ingredients: The active ingredient in Indomethacin Capsule IP 25mg is indomethacin. Each capsule typically contains 25mg of indomethacin, along with inactive ingredients such as lactose, corn starch, magnesium stearate, and gelatin.

Mechanism of Action: Indomethacin works by inhibiting the production of prostaglandins, which are chemicals in the body that contribute to inflammation, pain, and fever. By blocking the action of these prostaglandins, indomethacin helps reduce pain and inflammation associated with various conditions.

Usage: Indomethacin Capsule IP 25mg is usually taken orally with food or milk to reduce the risk of stomach upset. The dosage and duration of treatment may vary depending on the condition being treated, the severity of symptoms, and individual response to the medication. It is important to take indomethacin exactly as prescribed by a healthcare professional.

Precautions: Before taking Indomethacin Capsule IP 25mg, inform your healthcare provider if you have any allergies to medications, especially NSAIDs. Indomethacin may increase the risk of serious cardiovascular events such as heart attack or stroke, particularly in individuals with a history of heart disease or risk factors for cardiovascular disease. It may also cause gastrointestinal side effects such as stomach ulcers or bleeding. Use caution when taking indomethacin in combination with other medications that may increase the risk of these side effects, such as corticosteroids or anticoagulants.

Side Effects: Common side effects of Indomethacin Capsule IP 25mg may include stomach pain, nausea, vomiting, diarrhea, headache, dizziness, and drowsiness. Less common but more serious side effects may include gastrointestinal bleeding, kidney problems, high blood pressure, and allergic reactions. Contact your healthcare provider if you experience any severe or persistent side effects while taking indomethacin.

Duration of Treatment: The duration of treatment with Indomethacin Capsule IP 25mg varies depending on the condition being treated and the individual response to the medication. It is important to continue taking indomethacin as prescribed, even if symptoms improve, unless otherwise directed by a healthcare professional.

Consultation: Before starting treatment with Indomethacin Capsule IP 25mg, consult with a healthcare professional to determine if it is suitable for your condition and to receive personalized treatment recommendations. Your healthcare provider may need to adjust the dosage or choose an alternative medication based on your individual circumstances.

Overall, Indomethacin Capsule IP 25mg can be an effective medication for the relief of pain and inflammation associated with various conditions when used under medical supervision and according to prescribed guidelines.

Indomethacin is used to reduce inflammation, pain, and fever. It's used to treat rheumatoid arthritis, osteoarthritis, gouty arthritis, and shoulder pain.

Topical Anti-Inflammatory & Pain Relief Gel

Product Overview:
Naproxen Gel 10% is a powerful non-steroidal anti-inflammatory drug (NSAID) in topical gel form, designed to relieve pain and reduce inflammation right at the source. This fast-absorbing gel is ideal for localized relief from musculoskeletal pain, arthritis, sprains, strains, and sports injuries. With a high concentration of 10% Naproxen, it provides effective symptomatic relief without the systemic side effects of oral NSAIDs.

Key Features & Benefits:
✅ High-strength 10% Naproxen formulation
✅ Fast-acting pain and inflammation relief
✅ Non-greasy and quickly absorbed
✅ Suitable for muscle, joint, and tendon pain
✅ Reduces swelling, stiffness, and discomfort

Indications for Use:

• Osteoarthritis and rheumatoid arthritis

• Back pain and sciatica

• Sprains, strains, and sports injuries

• Tendonitis and bursitis

• Muscular aches and joint pain

Directions for Use:
Apply a small amount of gel (about 1–2 grams) to the affected area 2 to 3 times a day. Massage gently into the skin until fully absorbed. Wash hands after application. Do not apply on broken or irritated skin.

Precautions:
⚠️ For external use only
⚠️ Avoid contact with eyes or mucous membranes
⚠️ Not suitable for children under 12 years without medical advice
⚠️ Do not use if allergic to Naproxen or other NSAIDs
⚠️ Consult your doctor if pregnant, breastfeeding, or using other medications

Possible Side Effects:

• Mild skin irritation or redness at the application site

• Rare allergic skin reactions (rash, itching)

• Photosensitivity in rare cases – avoid prolonged sun exposure

Storage Instructions:

• Store below 25°C

• Keep tube tightly closed

• Keep out of reach of children

Packaging:
📦 Tube: 30 grams
📦 Box packaging for retail and export
🛒 Bulk & OEM options available for distributors