Cardiac Drugs

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<p>Apixaban is a prescription medication belonging to a class of drugs known as anticoagulants, or blood thinners. It is primarily used to prevent blood clots in individuals at risk for stroke or systemic embolism, particularly those with atrial fibrillation, a type of irregular heartbeat. Here are some key points about Apixaban (5mg) tablets:</p> <ol> <li> <p><b>Anticoagulant Activity:</b> Apixaban works by inhibiting the activity of Factor Xa, a key enzyme involved in the blood clotting process. By blocking Factor Xa, Apixaban prevents the formation of blood clots, reducing the risk of stroke, systemic embolism, and other thrombotic events.</p> </li> <li> <p><b>Indications:</b> Apixaban is indicated for several medical conditions, including:</p> <ul> <li>Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation.</li> <li>Treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE).</li> <li>Reduction of the risk of recurrent DVT and PE following initial therapy.</li> </ul> </li> <li> <p><b>Dosage Form:</b> Apixaban is available in tablet form for oral administration. Each tablet typically contains 5mg of the active ingredient, apixaban. The tablets are film-coated for ease of swallowing and may be taken with or without food.</p> </li> <li> <p><b>Dosage Regimen:</b> The dosage of Apixaban may vary depending on the specific indication, the patient's medical history, and other factors. It is essential to follow the prescribed dosage regimen as directed by a healthcare professional. For stroke prevention in atrial fibrillation, the usual dose is 5mg taken orally twice daily.</p> </li> <li> <p><b>Monitoring and Adjustments:</b> Regular monitoring of kidney function and other relevant laboratory parameters may be necessary during treatment with Apixaban. Dose adjustments may be required in patients with impaired kidney function or other factors that may affect drug metabolism or clearance.</p> </li> <li> <p><b>Safety and Side Effects:</b> While generally well-tolerated, Apixaban may cause side effects in some individuals. Common side effects may include bleeding, bruising, gastrointestinal disturbances, and headache. Serious bleeding events, although rare, can occur and require immediate medical attention.</p> </li> <li> <p><b>Precautions and Contraindications:</b> Apixaban should be used with caution in patients with a history of bleeding disorders, gastrointestinal ulceration, or renal impairment. It is contraindicated in individuals with active pathological bleeding or a known hypersensitivity to the drug.</p> </li> <li> <p><b>Drug Interactions:</b> Apixaban may interact with other medications, including other anticoagulants, antiplatelet drugs, and certain medications metabolized by the cytochrome P450 enzyme system. It is essential to inform the prescribing healthcare provider of all medications, supplements, and herbal products being taken to avoid potential interactions.</p> </li> </ol> <p>Apixaban (5mg) tablets are an important therapeutic option for the prevention and treatment of thromboembolic disorders, offering efficacy and convenience in anticoagulant therapy. It is crucial to use Apixaban as directed and to adhere to regular monitoring and follow-up appointments to ensure safe and effective treatment outcomes.</p>